Thioredoxin has also been demonstrated to bind to ASK1 to inhibit its action for a kinase [32]. This inhibition is attenuated by ROS that may lead to dimerization of thioredoxin [33]. Thioredoxin regulation with the glucocorticoid receptor by means of Affiliation at the DNA binding domain has also been noted [34] and this as well is motivated by RO

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